SUPERCHARGED CHIMERIC ANTIGEN RECEPTOR T CELLS IN SOLID TUMORS

Supercharged chimeric antigen receptor T cells in solid tumors

decal Chimeric antigen receptor (CAR) T cells have demonstrated success in treating select hematological malignancies, but their activity in solid tumors has been comparably modest.Challenges specific to treating solid tumors include trafficking and distribution throughout the tumor site, overcoming the immunosuppressive tumor microenvironment (TME

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Targeted and Untargeted Metabolomics Profiling of Wheat Reveals Amino Acids Increase Resistance to Fusarium Head Blight

Fusarium head blight (FHB), a notorious plant disease caused by Fusarium graminearum (F.graminearum), is severely harmful to wheat production, resulting in a decline in grain quality and yield.In order to develop novel control strategies, metabolomics has been increasingly used to characterize more comprehensive profiles of the mechanisms of underl

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